JAVIER SZWARCBERG,WILLIAMSON ZIEGLER BRADFORD,SZWARCBERG JAVIER,BRADFORD WILLIAMSON ZIEGLER
申请号:
BRPI0921022
公开号:
BRPI0921022A2
申请日:
2009.11.09
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone administration. The methods include administering to a patient pirfenidone at doses lower than the full target dosage for a time period, followed by administering to the patient pirfenidone at the full target dosage. The methods also include administering pirfenidone at the full target dose with no reduction and administering permanently reduced doses of pirfenidone.