Samuel Helmer Gellman,Pil Seok Chae,Philip D. Laible,Marc J. Wander
申请号:
US12420701
公开号:
US08263754B2
申请日:
2009.04.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides amphiphiles for manipulating membrane proteins. The amphiphiles can feature carbohydrate-derived hydrophilic groups and branchpoints in the hydrophilic moiety and/or in a lipophilic moiety. Such amphiphiles are useful as detergents for solubilization and stabilization of membrane proteins, including photosynthetic protein superassemblies obtained from bacterial membranes.