Horst G. Zerbe,Nadine Paiement,Cormac Long,Rodolphe Obeid
申请号：
US15848819
公开号：
US20180110724A1
申请日:
2017.12.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Oral film dosage forms that provide improved solubilization and stabilization of an active ingredient in particle form include at least one primary crystallization inhibitor in an amount that inhibits growth and/or agglomeration of the active ingredient, a polyoxyethylated fatty acid glycerides in an amount that further enhances inhibition of crystallization, growth and agglomeration of the particles of the pharmaceutically active ingredient and at least one plasticizer present in an amount that is effective to increase flexibility and elasticity of the film dosage form.
