A pathology localizer and therapeutical procedure guide system comprising an elongate strip (1) provided with an array of three linear columnar members (2,3,4) having a common point of origin (O) at one end of strip (1) and extending divergently to corresponding ends (X,Y,Z) at the other end thereof. These linear columnar members (2,3,4) are equipped with a contrast medium visible in imaging modalities of a body portion with strip (1) placed thereupon, thereby producing an array of visible imprints of three linear segments (OX), (OZ), (OY) in a frontal X-Ray image and a series of visible imprints of three sequential spots (X1,Z1,Y1) in a sectional CT or MRI image, wherein these visible imprints are used in precisely determining the locus of a pathology, if any, identified within the body portion being scanned and in subsequently determining an accurately defined path of instrumentation adapted to effect a therapeutical procedure therein.
