#$%^&*AU2019204921A120190801.pdf#####62 ABSTRACT METHOD The present invention relates to a chimeric antigen receptor (CAR) which comprises an antigen-binding domain which selectively binds TCR beta constant region 1 (TRBC1) or TRBC2; cells; such a T cells comprising such a CAR; and the use of such cells for the treatment of a T-cell lymphoma or leukaemia in a subject.1/27 VB Va CB Ca CD36 CD3y CD3E CD3( CD3( CD3E FIG. 1