The present invention includes a method of treating prostate cancer in a human subject in need thereof, comprising administering to the subject an effective amount of a composition comprising interleukin-2 (IL2), and administering to the subject a cell expressing a chimeric antigen receptor (CAR) which specifically binds prostate specific membrane antigen (PSMA), thereby treating prostate cancer in the human subject in need thereof.本發明包括治療有需要之人類個體中前列腺癌之方法,其包含向該個體投與有效量之包含介白素-2(interleukin-2;IL2)之組合物及向該個體投與表現特異性結合前列腺特異性膜抗原(prostate specific membrane antigen;PSMA)之嵌合抗原受體(chimeric antigen receptor;CAR)之細胞,由此治療需要其之該人類個體中的前列腺癌。