Smith, Jeffrey T.L.,Feldhaus, Andrew L.,Garcia-Martinez, Leon R.
申请号：
AU2019250228
公开号：
AU2019250228A1
申请日:
2019.10.18
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
#$%^&*AU2019250228A120191107.pdf#####ABSTRACT The present invention is directed to therapeutic methods using IL-6 antagonists such as anti-IL-6 antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat mucositis (e.g., oral mucositis) including persons on a treatment regimen with a drug or chemotherapy and/or radiation for cancer (e.g., head and neck cancer) that is associated with increased risk of mucositis, including oral mucositis.JFra；:, 1/29 1 1,P. 066 2ZZ 000 oa ooo 0N F-~ L ~00 wLU 0-0on 0 zzz z_ Ono LBL -UJ~ aj C-02 U) 2 co - z zz z - 2-ZZ 2 - - _So 0 0z~i Q <； >；->；-；' to 0e >； a-<；-<； ix-xx <； U-t 0=20 _ 0 <； >；0 (/)- U) W COLOC u02 -4 U5 i U-E)E -O a- z2 o--o O _ 0-o 0 LLsa a=4YY e yy e le N rl_ Cr a. C C r ( 0 <； 6<； oq 000 a 0-000 cc of 01 ce I ml 0 z 0lO 6AIEzI g jzroz Oo-o mc al z z C-ocW (0 w Q C O n 2 N 0 (02 >； -I - B r O=<；-c8'CC a 202 c Y) V5 pi 8w a wd w- s . U- U- w w 0'am0e-cC a a o 0-00 CD -0 -0 (0 vi0 0-000 0= a -0 >；- i >；5xFla-~ N N U) n a a- aC >；- <；2C <； - <； >； >；0 ( >； 4 -j _j (-0 aU l)0 2 F-- L4O"- 0( (<；- CO CO( & C 0 w VwQ F- 0 U)C t--_ F-F- r _ J 00o00:( 0 m CO2- >； O >；- F5 >； o 0 ) trA 0 F- a0 C 0-Oc<； 0) o00 3 aa >；q I I~ C0?L CO~~~ F-->；F -''D0 <；~~~~ 0222 20 -o aao~~~~a a TO0COF-~~ 0220 02 02 >；J-ww
