salts and polymorphs of sulfamide ns3 inhibitors

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专利权人:

NOVARTIS AG

发明人:

LIJUN ZHANG,LIPA SHAH,PAUL ALLEN SUTTON

申请号：

BR112013008388

公开号：

BR112013008388A2

申请日:

2011.10.08

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

The invention provides new salts and polymorphs of (5R,8S)-7-[(2S)-2-{[(2S)-2-cyclohexyl-2-({[(2S)-1-isopropylpiperidin-2-yl]carbonyl}amino)acetyl]amino}-3,3-dimethyl butanoyl]-N-{(1R,2R)-2-ethyl-1-[(pyrrolidin-1-ylsulfonyl)carbamoyl]cyclopropyl}-10,10-dimethyl-7-azadispiro[3.0.4.1]decane-8-carboxamide (referred to herein as Compound X), pharmaceutical compositions containing them and processes for their manufacture and use in therapy.

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