LI ZHONG,SERGEI ZOLOTUKHIN,MAVIS AGBANDJE-MCKENNA,ARUN SRIVASTAVA,LAKSHMANAN GOVINDASAMY
申请号:
PT08733161
公开号:
PT2191001T
申请日:
2008.04.08
申请国别(地区):
PT
年份:
2016
代理人:
摘要:
Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of rAAV vectors.