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Pharmaceutical compositions of water soluble peptides with poor solubility in isotonic conditions and methods for their use
专利权人:
Strongbridge Biopharma plc
发明人:
Michel Afargan
申请号:
US15487731
公开号:
US10039801B2
申请日:
2017.04.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides compositions comprising water soluble peptides with poor solubility in isotonic solutions which exhibit enhanced bioavailability with reduced adverse effects including injection site reactions. Methods are also disclosed for using such compositions for the treatment of diseases including, but not limited to, cancer, type 2 diabetes, acromegaly, metabolic disorders, endocrine disorders, exocrine tumors, and hormone-related tumors. Methods to reduce adverse injection site reactions and improve bioavailability are also disclosed.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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