PATEL, KETAN R.,PATEL, MILAN R.,PATEL, ASHEEL K.,SHAH, PRAKASHCHANDRA J.
申请号:
CA2969303
公开号:
CA2969303A1
申请日:
2015.11.17
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to low volume intravenous injections of paracetamol or its pharmaceutically acceptable salt and method of preparation thereof. The formulations provide high concentration of paracetamol or its pharmaceutically acceptable salt in a solvent system of the present invention which can be administered not only through intra- muscular & intravenous infusion route but also suitable for slow IV bolus administration after dilution with aqueous fluids to final volume of not more than 20 ml. These injectable formulations remain stable and are also suitable for administration through slow intravenous route with minimized side effects (such as phlebitis, pain etc.).