Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation

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专利权人:

Curevac GmbH

发明人:

Baumhof, Patrick,Voss, Sohnke,Kramps, Thomas,Kallen, Karl-Josef

申请号：

AU2011285200

公开号：

AU2011285200B2

申请日:

2011.07.25

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The present invention is directed to a polymeric carrier cargo complex, comprising as a cargo at least one nucleic acid (molecule) and disulfide-crosslinked cationic components as a (preferably non-toxic and non-immunogenic) polymeric carrier. The inventive polymeric carrier cargo complex allows for both efficient transfection of nucleic acids into cells

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