A self-sealing dressing (10) adapted for negative pressure wound therapy, for application on the skin of a human being in the form of a laminate comprising: a substrate (12) having an upper surface (14) and a surface (16 ) posterior； and an adhesive layer (18) disposed on at least a part of the back surface (16) of the substrate (12)； the substrate (12) that includes an elastomeric material； and the adhesive layer (18) which is a cold-flowing silicone shear thinning gel coupled to the substrate (12) and adapted to adhere to the skin of a human to form a substantially gas-impermeable seal between the layer ( 18) adhesive and the skin that is maintained for at least one repeated flexion or extension of the dressing (10), wherein a maximum thickness of the combination of the substrate (12) and the adhesive layer (18) is approximately 25 μm； and wherein the substrate (12) has a thickness that extends between the upper and rear surfaces (14, 16), and an opening (30) is defined that extends through a total thickness of the substrate (12), the opening (30) that is exposed on the rear surface (16) of the substrate (12) that faces the adhesive layer (18).Un apósito (10) autosellante adaptado para terapia de herida de presión negativa, para aplicación en la piel de un ser humano en forma de un laminado que comprende: un sustrato (12) que tiene una superficie (14) superior y una superficie (16) posterior； y una capa (18) adhesiva dispuesta sobre al menos una parte de la superficie (16) posterior del sustrato (12)； el sustrato (12) que incluye un material elastomérico； y la capa (18) adhesiva que es un gel de silicona de adelgazamiento por cizalladura que fluye en frío acoplado al sustrato (12) y adaptado para adherirse a la piel de un humano para formar un sello sustancialmente impermeable a los gases entre la capa (18) adhesiva y la piel que se mantiene durante al menos una flexión o extensión repetida del apósito (10), en donde un espesor máximo de la combinación del sustrat
