The present invention relates to the new applications of neohesperidin. Specifically, the plant extracts the present invention relates to neohesperidin or comprising neohesperidin improves and/or promote skin microcirculation with what in preparation, or eliminates and/or alleviate and the purposes in the product of the bad related illness of skin microcirculation or state. The invention further relates to the compositions of the plant extracts comprising a effective amount of neohesperidin or comprising neohesperidin, and improve and/or promote skin microcirculation using neohesperidin, or eliminate and/or alleviate the method with the bad related illness of skin microcirculation or state. Present invention discover that neohesperidin can be beneficial to the especially eye part skin microcirculation of what skin microcirculation.本發明涉及新橙皮苷的新用途。具體地說,本發明涉及新橙皮苷或包含新橙皮苷的植物提取物在製備用於改善和/或促進皮膚微循環,或者消除和/或緩解與皮膚微循環不良有關的病症或狀態的産品中的用途。本發明還涉及包含有效量的新橙皮苷或包含新橙皮苷的植物提取物的組合物,以及使用新橙皮苷改善和/或促進皮膚微循環,或者消除和/或緩解與皮膚微循環不良有關的病症或狀態的方法。本發明發現新橙皮苷可以有益於皮膚微循環特別是眼部皮膚微循環。