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New 5,7-disubstituted derivatives of [1,3] thiazolo [4,5-d] pyrimidin-2 (3H) -one and its use in therapy
专利权人:
ASTRAZENECA AB
发明人:
JOHANSSON, ROLF,KARLSTROEM, SOFIA,KERS, ANNIKA,NORDVALL, GUNNAR,REIN, TOBIAS,SLIVO, CAN
申请号:
ES07835061
公开号:
ES2377469T3
申请日:
2007.09.27
申请国别(地区):
ES
年份:
2012
代理人:
摘要:
A compound of formula (I) (I) wherein: R1 represents CH3 or CF3; R2 represents halo, CN or C1-6 alkyl; R3 represents H or CH3; R4 represents H or CH3; n represents 0, 1 or 2, where the term "C1-6 alkyl" includes both straight and branched chain and cyclic alkyl groups; as a free base or a pharmaceutically acceptable salt, solvate or solvate of a salt.Un compuesto de fórmula (I) (I) donde:R1 representa CH3 o CF3; R2 representa halo, CN o alquilo C1-6; R3 representa H o CH3; R4 representa H o CH3; n representa 0, 1 ó 2, donde el término "alquiloC1-6" incluye tanto grupos alquilo de cadena lineal y ramificada como también cíclicos; como una base libre o una de sus sales, solvatos o solvatos de una sal farmacéuticamente aceptables.
来源网站:
中国工程科技知识中心
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