The various implementations disclosed and contemplated herein relate to methods, systems, and devices for reducing or eliminating the pain of various procedures that pierce or otherwise generate pain in a patients skin. Specific embodiments relate to devices and systems having at least two stimulation components that stimulate the target area with at least one of vibration and electrical stimulation. Some embodiments include stimulation components that are positioned on the fingers of the user, while other embodiments include a syringe-receiving component with stimulation components on flexible arms extending from the syringe-receiving component.