Lapina, Olga Viktorovna,Shi, Bing,Wang, Fang,Wolckenhauer, Scott Alan
申请号：
AU2018201948
公开号：
AU2018201948A1
申请日:
2018.03.19
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018201948A120180412.pdf#####1002109511 ABSTRACT Crystalline solid forms of methyl {(2S)-1-[(2S,5S)-2-(9-{2-[(2S,4S)-1- {(2R)-2[(methoxycarbonyl)amino]-2-phenylacetyl } -4-(methoxymethyl)pyrrolidin-2-yl] -1 H-imidazol-5-yl}1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-2-yl)-5-methylpyrrolidin-1-yl]-3methyl-1-oxobutan-2-yl}carbamate (Compound I) were prepared and characterized in the solid state: H3CO H 0~NH C N-N(N HN 0 H3CO OCH3 Compound I Also provided are processes of manufacture and methods of using these crystalline forms.
