Albino Manuel Pereira Martins,Marta Luísa Sousa Dias Alves Da Silva,Rui Luís Gonçalves Dos Reis,Nuno João Meleiro Alves Das Neves
申请号：
US15993020
公开号：
US20180272038A1
申请日:
2018.05.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present application describes a polymeric mesh for the repair and regeneration of tissues from an organism that comprises pores wherein at least 70% of the pores of the said mesh have a size smaller than the one required to confine the cells of the said tissues, and wherein at least 70% of the pores of the said mesh has a size superior than the one needed for the passage of interstitial fluids of the said tissues the degradation time of the said polymeric mesh within the organism is at least 8 weeks the said polymeric mesh has an apparent tensile strength superior than 1 MPa the said polymeric mesh has an apparent elastic modulus superior than 0.1 MPa. The mesh described in this application allows that the “new tissue” formed presents very similar properties to the ones of the damaged tissue.Thus, the polymeric mesh for the repair and regeneration of tissues described in this application can be used in medicine in combination or not with surgical methods, namely in the treatment of diseases that involve the repair and regeneration of tissues, particularly when the tissue to treat is cartilage, periodontal ligament, esophagus or skin.
