This present invention relates to fungal immunomodulatory proteins, compositions and method for use in immunotherapy, treating or preventing cancer due to metastasis or suppression of telomerase activity by down-regulation of the telomerase catalytic subunit (hTERT), activating natural killer cells, macrophage or increasing serum antibody. The present invention also relates to a kit for use in detecting the cancer due to metastasis or suppression of telomerase activity by down-regulation of the telomerase catalytic subunit (hTERT).本發明關於真菌免疫調節蛋白使用於免疫治療、治療及預防由於轉移產生的癌症、或藉由抑制端粒酶催化次單位(hTERT)來壓抑端粒酶活性的癌症、活化自然殺手細胞、巨噬細胞或增加血清抗體治療等的組成及方法。本發明另關於用來偵測由於轉移產生的癌症,或藉由抑制端粒酶催化次單位來壓抑端粒酶活性的癌症。
