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Quinolone M1 receptor positive allosteric modulators
专利权人:
William D. Shipe
发明人:
William D. Shipe,Craig Lindsley,David Hallett
申请号:
US11920717
公开号:
US08389545B2
申请日:
2006.12.04
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to quinolone compounds of general formula (I)which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimers disease, pain or sleep disorders, and to novel M1 receptor positive allosteric modulator compounds of formulae (II) to (VIII). The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases in which the M1 receptor is involved.
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