Anticorps inhibitants se liant au complex de l'activateur du plasminogene de type urokinase (uPA) et son recepteur (uPAR)

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专利权人:

TACTIC PHARMA; LLC

发明人:

申请号：

EP05754219.3

公开号：

EP1765397B1

申请日:

2005.05.25

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Antibodies or other ligands specific for the binary uPA-uPAR complexes, for ternary complexes comprising uPA-uPAR and for complexes of uPAR and proteins other than uPA such as integrins inhibit the interaction of uPA and uPAR with additional molecules with which the complexed interact. Such antibodies or other ligands are used in diagnostic and therapeutic methods, particularly against cancer.

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