The present invention relates to oxazolidin-2-one substituted pyrimidine compounds that act as PI3K (phosphatidylinositol-3-kinase) inhibitors, as well as pharmaceutical compositions thereof, methods for their manufacture and uses for the treatment of conditions, diseases and disorders dependent on PI3K.本發明係關於充當PI3K(磷脂醯肌醇-3-激酶)抑制劑之經唑烷-2-酮取代之嘧啶化合物,以及其藥物組合物,製造其之方法及用於治療與PI3K有關之病狀、疾病及病症的用途。