Jonathan Ee-Ren Lim,Pratik S. Multani,Richard Landin,Rupal Patel,Jennifer Wright Oliver
申请号:
US16466005
公开号:
US10799503B2
申请日:
2017.11.29
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are methods of treating cancer in a subject, wherein the subject is known to possess at least one genetic alteration in RET, comprising administering to the subject a therapeutically effective amount of N-[3-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N′;-[5-(2,2,2-trifluoro-1, 1-dimethylethyl)-3-isoxazolyl]-urea, or a pharmaceutically acceptable salt thereof.