BEHRENS, TIMOTHY W.,OWCZARCZYK, KASIA,TOWNSEND, MICHAEL J.
申请号:
EP12752355
公开号:
EP2680884A4
申请日:
2012.02.27
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Biological markers that predict patient responsiveness to B-cell antagonists are provided. Also provided are methods of using such biological markers. In addition, methods for identifying patients suffering from an autoimmune disease, e.g., rheumatoid arthritis, who are not likely to respond to B-cell antagonists are provided, as are methods of treating such patients. Methods for selecting therapeutic agents to treat such patients are also provided.