The present invention relates to the spore of Ganoderma Lucidum having an effect of losing weight and, more specifically, the spore of Ganoderma Lucidum, users take, which prevents weight of the users who eat rich fat and high cholesterol meals from being increased and accordingly decreases the increase of fat in the human body wherein the spore of Ganoderma Lucidum used in the present invention is from a biological science research center in Chongqing province, China and had no an additional extraction process and a pre-treatment process to check whether the spore of Ganoderma Lucidum has effects of losing weight or not in a pre-clinical test.본 발명은 영지포자의 체중감소 효과에 관한 것으로, 보다 자세하게는 영지포자의 섭취를 통해 고지방 및 고콜레스테롤 식이에 따른 체중의 증가가 예방되고, 이에 따른 체내 지방의 증가가 감소 되는 효과에 관한 것이다.