DAHL, SHANNON L.M.,NIKLASON, LAURA E.,BLUM, JULIANA,STRADER, JUSTIN T.,TENTE, WILLIAM E.,PRICHARD, HEATHER L.,LUNDQUIST, JOSEPH J.
申请号:
CA2822689
公开号:
CA2822689C
申请日:
2012.01.06
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention provides effective, rapidly available, reliable and cost-effective tissue engineered constructs including a tubular biodegradable non-wovenpolyglycolic acid scaffold, wherein the scaffold may be coated withextracellular matrixproteins and substantially acellular. The constructs function long term withminimal tono side effects upon implantation and can be utilized as an arteriovenousgraft, acoronary graft, a peripheral artery bypass conduit, or a urinary conduit. Thepresentinvention also provides methods of producing such constructs.