BISPECIFIC ANTIBODY TARGETING HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR

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专利权人:

发明人:

Izumi KUMAGAI,Ryutaro ASANO,Mitsuo UMETSU

申请号：

US15310358

公开号：

US20170274072A1

申请日:

2015.02.25

申请国别(地区):

US

年份:

2017

代理人:

摘要：

To provide bispecific antibodies and highly functional bispecific antibodies, which are produced by using a new anti-human EGF receptor 1 (Her 1) antibody different from the antibody 528. A bispecific antibody, comprising a variable region of the light chain (2L: SEQ ID NO:2) and a variable region of the heavy chain (2H: SEQ ID NO:4) of an anti-human EGF receptor 1 antibody 225, and a humanized variable region of the light chain (OL: SEQ ID NO:6) and a humanized variable region of the heavy chain (OH: SEQ ID NO:8) of an anti-CD3 antibody OKT, and the like.

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中国工程科技知识中心

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http://www.ckcest.cn/home/