Xenoantigen-Displaying Anti-Cancer Vaccines and Method of Making

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专利权人:

THE UNIVERSITY OF TOLEDO

发明人:

Steven J. Sucheck,Katherine A. Wall,Sourav Sarkar

申请号：

US14378805

公开号：

US20150024037A1

申请日:

2013.02.15

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Compositions, methods of making, and methods of using, xenoantigen-displaying anticancer vaccines are described. In another broad aspect, there is provided herein a method of synthesizing an alkynefunctionalized composition of claim 1, comprising: deprotecting an ester comprising a Fmoc moiety to form a free acid； coupling the free acid of step (a) with an amine； and, removing the Fmoc moiety, and coupling the remaining moiety with palmitic acid to yield an alkyne-functionalized composition.

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