An integrated ocular fluid management system that, in one instance, includes a first chamber connected to a first input line and a first output line. A second chamber is connected to a second input line and a second output line. A first pump communicates with the first output line. A second pump communicates with the second input line. A first pressure regulator communicates with the first chamber. A second pressure regulator communicates with the second chamber. A first diaphragm is in the first chamber and a second diaphragm is in the second chamber. A first controller controls at least one of the first pump and the first pressure regulator to maintain the first diaphragm in a predetermined position. A second controller controls operation of at least one of the second pump and the second pressure to maintain the second diaphragm in a predetermined position.