The present invention relates to a compound represented by the following formula, a pharmacologically acceptable salt thereof, or a use thereof as a harmaceutical:wherein R1and R2are substituents adjacent to each other, and together with two carbon atoms to each of which they attach, form a 5－to 7－membered non－aromatic carbocyclic group or the like, which may be substituted by 1 to 4 substituents selected from (1) an oxo group, (2) a hydroxyl group, and the like；R3represents a hydrogen atom or the like；and R6represents a hydrogen atom or the like.It is an object of the present invention to discover an agent for treating or preventing lower urinary tract symptoms, and particularly symptoms regarding urinary storage, which has a superior strength of binding to a 5－HT1A receptor and an antagonism to the receptor.本發明係有關於一種以下列化學式表示之化合物，其藥理可接受鹽，或其作為藥物之使用：其中，R1及R2係彼此相鄰之取代基，且與和其附接之二碳原子一起，形成5－至7－員之非芳香族碳環基等，其可以1至4個選自(1)氧基，(2)羥基等之取代基取代；R3代表氫原子等；且R6代表氫原等。本發明之一目的係發現用於治療或預防下泌尿道徵侯群且特別是關於尿液儲存之徵候之藥劑，其具有較優之與5－HT1A受體接合之強度及對此受體之拮抗性。
