SYSTÈMES DE DÉLIVRANCE DE MÉDICAMENT À LIBÉRATION SOUTENUE COMPRENANT UN AGENT THÉRAPEUTIQUE SOLUBLE DANS L'EAU ET UN AGENT DE MODIFICATION DE LIBÉRATION
The present invention relates to a sustained release drug delivery system comprising: (a) a water soluble therapeutic agent; (b) a polymeric carrier for the therapeutic agent; and (c) a release modifier for modifying a release rate of the therapeutic agent from the polymeric carrier, wherein the release modifier is an aliphatic alcohol, and the sustained release drug delivery system can release a therapeutic amount of the therapeutic agent over a period of time of at least about one week, wherein the therapeutic agent is adalimumab.