PIANOWSKI, LUIZ FRANCISCO,CALIXTO, JOAO BATISTA,LEAL, PAULO CESAR,CHAVES, CLAUDIO PAULINO
申请号：
NZ59023308
公开号：
NZ590233A
申请日:
2008.08.05
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Use of one or more lanosta-8,24-dien-3-oIs in the manufacture of a medicament suitable for administration to a mammalian subject for the treatment of pain is disclosed, wherein said pain is linked to the disordered activation of serine-threonine protein kinases, wherein said medicament inhibits the increased or reduced activation of serine-threonine protein kinases, or the transcription factors modulated by them and wherein said lanosta-8,24-dien-3-oIs are selected from euphol, tirucallol and lanosterol, or the isomers, derivatives, solvates or hydrates, or mixture thereof.
