TIMOTHY J CHURCH,JOHN R JACOBSEN,LAN JIANG,IOANNA STERGIADES,PRISCILLA VANDYKE,SEAN DALZIEL,LETICIA PREZA,DANIEL D LONG,DAISUKE ROLAND SAITO
申请号:
IN7750/DELNP/2008
公开号:
IN280975B
申请日:
2008.09.15
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The invention provides novel 8-azabicyclol[3.2.1]oc-tane compounds of formula (I) wherein R1 , R2 , R3 , A, and G are defined in the specification, or a pharmaceutically-acceptable salt or solvate thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and