Choline esterase inhibiter and selective serotonin it re-took in and it possesses the high curative effect where new it becomes the inhibiter, the mil it does not become combining with plan or deyurokisechin you disagree the medicine composition was superior markedly former you disagree in comparison with the medicine. The remedy method using choline esterase inhibiter and selective serotonin re-of taking in and the inhibiter, the mil it does not become combining with plan or deyurokisechin, the melancholia, especially, is useful in remedy of the difficult Osamu characteristic melancholia.コリンエステラーゼ阻害剤と、選択的セロトニン再取り込み阻害剤、ミルナシプラン又はデュロキセチンとを組合せてなる新規抗うつ剤組成物は、従来の抗うつ剤と比べ格段に優れた高い治療効果を有する。コリンエステラーゼ阻害剤と、選択的セロトニン再取り込み阻害剤、ミルナシプラン又はデュロキセチンとを組み合わせて用いる治療方法は、うつ病、特に、難治性のうつ病の治療に有用である。
