The University of Vermont and State Agricultural College
发明人:
Yvonne M. Janssen-Heininger,Vikas Anathy
申请号:
US15874136
公开号:
US20180221436A1
申请日:
2018.01.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention generally relates to systems and methods for treating certain oxidative stress conditions. In one aspect, compositions and methods of the invention can be used to treat a subject having an oxidative stress condition, for example, a subject having pulmonary fibrosis. In some embodiments, an inhibitor of ERp57 (for example, thiomuscimol) and/or an inhibitor of GSTP (for example, TLK-199) may be used to treat the subject. Also provided in certain aspects of the present invention are kits for such therapies, methods for promoting such therapies, and the like.