Kai Schiemann,Melanie Schultz,Wolfgang Staehle,Ingo Kober,Dirk Wienke,Mireille Krier
申请号:
US13132181
公开号:
US08530650B2
申请日:
2009.11.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to pyridopyrimidine derivatives according to formula (I) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers.