ВАДРЕВУ Кришна Мохан (IN),ПРАСАД Сай Девараджулу (IN)
申请号：
RU2014146772
公开号：
RU2014146772A
申请日:
2013.04.23
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. A liquid formulation of the vaccine, soderzhaschiyi. rotavirus antigen ii. a combined buffering system iii. combination of sugars iv. recombinant human serum albumin v. partially hydrolyzed protein hydrolyzate laktalbumina.2. Vaccine composition according to Claim. 1, where a combined buffering system is a citrate-bicarbonate buffer sistemu.3. Vaccine composition according to claim. 2, wherein the citrate concentration is in the range of from 0.01 to 0.05 M.4. Composition according to claim vaccine. 2, wherein the concentration of bicarbonate is in a concentration range of 0.01 to 2 M.5. Vaccine composition according to claim. 3, wherein the concentration of citrate is 0.03 M.6. Vaccine composition according to claim. 4, wherein the concentration of bicarbonate is 0.3 M.7. Vaccine composition according to Claim. 1, where the combined buffer system is a carbonate-bicarbonate buffer sistemu.8. Composition according to claim vaccine. 7, where the concentration of carbonate-bicarbonate buffer is in the range from 0.01 to 0.5 M.9. Vaccine composition according to claim. 8, wherein the carbonate-bicarbonate buffer is present at a concentration of 0.1 M.10. Vaccine composition according to claim. 8, wherein the carbonate-bicarbonate buffer is present at a concentration of 0.2 M.11. Vaccine composition according to Claim. 1, where the combined buffer system is a buffer system with magniya.12 hydroxycarbonate. Vaccine composition according to claim. 11 wherein the buffer system combined with magnesium hydroxycarbonate is in the concentration range from 0.01 to 0.5 M.13. Vaccine composition according to claim. 12 wherein the magnesium hydroxycarbonate is present at a concentration of 0.1 M.14. Composition according to claim vaccine. 1, where a combined buffering system is a mixed buffer system comprising of ammonium acetate, ammonium bicarbonate and diammonium ortofosfat.15. Vaccine composition according to claim. 14 wherein the buffer is mixed in a concentration range of
