Paolo P. Provenzano,Patricia Jo Keely,Kevin W. Eliceiri,John G. White
申请号：
US12040013
公开号：
US08144966B2
申请日:
2008.02.29
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention broadly provides methods and systems for detecting, identifying, and characterizing conditions, including diseases and other disorders in human or other animal subjects, by analyzing fluorescence from endogenous flavin adenine dinucleotide (FAD) fluorophors present in biological materials and samples. In particular embodiments, the invention relates to conditions of the human breast including cancers such as carcinoma. Methods and systems are provided for detecting, locating, and characterizing tumors and precancerous tissue via nonlinear optical imaging techniques capable of accurately characterizing fluorescence intensities and fluorescent lifetime parameters from endogenous FAD fluorophors present in a test tissue sample.
