MR UMAKANT VERMA,MR GOKUL A KHAIRNAR,MR RAHUL RAJPUT,DR RAJIB BANDYOPADHYAY,DR NABARUN BHATTACHARYYA,DR JITENDRA B NAIK
申请号:
IN201721002522
公开号:
IN201721002522A
申请日:
2017.01.23
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention describes a pharmaceutical composition with enhance bioavailability for oral administration in powder form where in taste of the active pharmaceutical ingredient is masked by Spray drying technique. The pharmaceutical composition comprising the glycyrrhizin and polyvinyl pyrrolidone K-30, which is used as taste masking agent for the unpleasant drug. The composition contains taste masked active pharmaceutical ingredient (Efavirenz), Xanthan gum and other pharmaceutically acceptable ingredients and the said pharmaceutical composition is homogeneously distributed for extended period of when dispersed in suitable suspending agent. Further, the taste masked antiviral formulation of the present invention is provided in the form of oral suspension wherein the bitter taste of efavirenz is masked there by providing palatable formulations.