BISSANTZ, CATERINA,BONNAFOUS, RENE,BUETTELMANN, BERND,JAKOB-ROETNE, ROLAND,LERNER, CHRISTIAN,RUDOLPH, MARKUS
申请号：
CA2886139
公开号：
CA2886139A1
申请日:
2013.12.23
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to compounds of formula (I), wherein the substituents are described in claim 1 and to the pharmaceutically acceptable salts thereof. These compounds inhibit the enzyme catechol-O-methyltransferase (COMT). The compounds may be used for the treatment of Parkinson's disease, depression, cognitive impairment and motor symptoms, resistant depression, cognitive impairment, mood and negative symptoms of schizophrenia.
