Kiyoshi Tachikawa,Joseph E. Payne,Padmanabh Chivukula
申请号：
US15859571
公开号：
US20180135051A1
申请日:
2017.12.31
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This invention provides pharmaceutical compositions containing a UNA oligomer targeted to TTR and a pharmaceutically acceptable carrier. The compositions can be used in methods for treating or preventing TTR-related amyloidosis in a primate. The compositions, upon administering a single dose to the primate, can reduce TTR protein in the primate for a period of days to weeks.
