synthesis process, and crystalline form of 4- {3- [cis-hexahydrocyclopenta [c] pyrrol-2 (1h) -yl] propoxybenzamide hydrochloride and pharmaceutical compositions containing the same
NICOLAS ROBERT,JEAN-MICHEL LERESTIF,JEAN-PIERRE LECOUVE,MARINA GAILLARD,LOIC MEUNIER,PHILIPPE LETELLIER,MATHIEU BOIRET
申请号：
BR102012013573
公开号：
BR102012013573A2
申请日:
2012.06.05
申请国别(地区):
BR
年份:
2013
代理人:
摘要：
SYNTHESIS PROCESS, AND CRYSTALINE 4- {3- [CIS-HEXA-HYDROCYCLOPENTA [C] PIRROL-2 (1H) -IL] PROP® XI} BENZAMIDE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. The present invention relates to industrial synthesis process and crystalline form I for the compound of formula (I)； and also the crystalline form I of the associated free base.PROCESSO DE SÍNTESE, E FORMA CRISTALINA DE CLORIDRATO DE 4-{3-[CIS-HEXA-HIDROCICLOPENTA[C]PIRROL-2(1H)-IL]PROPà XI}BENZAMIDA E COMPOSIÇÕES FARMACÊUTICAS CONTENDO O MESMO. A presente invenção refere-se a processo de síntese industrial, e forma cristalina I, para o composto da fórmula (I)； e também a forma cristalina I da base livre associada.
