Xi Chen,Pingchen Fan,Yandong Li,Jay P. Powers,Viengkham Malathong,Sreenivas Punna,Hiroko Tanaka,Penglie Zhang,Dean Dragoli
申请号：
US14099541
公开号：
US09328116B2
申请日:
2013.12.06
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
