PROBLEM TO BE SOLVED: To provide an agent inhibiting binding of BAFF to a BR3 receptor, and showing excellent preventive and therapeutic effect to acquired immune deficiency syndrome.SOLUTION: The inhibitor of binding of BAFF to a BR3 receptor contains a compound represented by general formula (1) [in the formula, R1 and R2 each represent an alkyl group Ar represents an aryl group X represents -O- or -NR4-, R3 represents a hydrogen atom and R4 represents a hydrogen atom or an alkyl group], or its salt, or solvates thereof as active ingredient.COPYRIGHT: (C)2012,JPO&INPIT【課題】BR3受容体に対するBAFFの結合を阻害し、後天性免疫不全症候群の予防及び治療効果に優れた薬剤を提供する。【解決手段】次の一般式(1):[式中、R1、R2は、アルキル基を、Arはアリール基を、Xは-O-又は-NR4-を、R3は水素原子を、R4は水素原子又はアルキル基を示す。]で表される化合物、若しくはその塩、又はそれらの溶媒和物を有効成分とするBR3受容体に対するBAFFの結合阻害剤。【選択図】なし
