INHIBITEUR D'ASGR DESTINE A REDUIRE LES TAUX DE CHOLESTEROL

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专利权人:

AMGEN INC.

发明人:

NIOI, PAUL,COWARD, PETER,MURAWSKY, CHRISTOPHER,PIPER, DEREK E.,GARCES, FERNANDO,ZHANG, JUN,LI, YANG,CHAN, BRIAN MINGTUNG

申请号：

CA2997444

公开号：

CA2997444A1

申请日:

2016.09.28

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Antigen binding proteins that interact with ASGR, ASGR-1 and/or ASGR-2 aredescribed as well as methods of makingand using such antigen binding proteins. Methods of treating and preventingcardiovascular disease by administering a pharmaceuticallyeffective amount of ASGR, ASGR-1 and/or ASGR-2 antigen binding proteins.Methods of treating and preventing cardiovasculardisease by administering a pharmaceutically effective amount of interferingRNA compositions that reduce expression ofASGR, ASGR-1 and/or ASGR-2 are described.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/