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RADIOPAQUE IODINATED PRODUCTS INTENDED FOR USE MEDICAL IMAGING AND THEIR METHODS
专利权人:
François Hallouard
发明人:
François Hallouard,Nicolas Anton,Guy Zuber,Thierry Vandamme,André Constantinesco,Philippe Choquet
申请号:
US13994250
公开号:
US20140065067A1
申请日:
2011.12.13
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Iodinated amphiphilic compound of formula (I):AG1-X—R  (I)wherein AG1 represents an unsaturated (C8-C52) aliphatic hydrocarbon chain found in fatty acids having specific location of double bonds, the chain including at least one iodine atom directly linked to a carbon atom of a non-conjugated double bond by a covalent link, the second carbon atom of the double bond bearing a halogen atom different from a iodine atom, X represents a polyethylene glycol including 1 to 50 ethylene glycol groups, R represents a hydrogen atom or a group AG2 being identical to or different from AG1, AG1, X, R and AG2 being selected so that the amphiphilic compound has a hydrophilic/lipohilic balance included between 4 and 30.
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