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CARBONIC ACID ADDUCTS
专利权人:
JENCLUSTER GMBH
发明人:
Beatrice Engert,Susanne Vogelsang
申请号:
US16644909
公开号:
US20200216384A1
申请日:
2018.09.07
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to a carbonic acid adduct (CAA) comprising carbonic acid, at least one amine, and optionally at least one salt, said adduct being producible by a method comprising the following steps: a) providing a solution (A) comprising dissolved CO2; optionally b) dissolving a base (BA) not corresponding to the amine (AM) in the solution (A) so as to obtain the solution (A1); c) dissolving the at least one amine (AM) in the solution (A) or (A1) so as to obtain the solution (B); d) freezing the solution obtained after completion of step c); and e) storing the solution frozen in step d) at −;100 to 0° C. for no longer than 4 days. The content of CO2 in the solution that is subjected to step c) is at least 6 g/l. The invention also relates to a method for producing the carbonic acid adduct (CAA), a pharmaceutical preparation (PP) comprising the carbonic acid adduct (CAA), and methods for the production thereof and use of the carbonic acid adduct (CAA) or the pharmaceutical preparation (PP) in therapy for a range of indications.
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