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Gene transfer agent
专利权人:
独立行政法人国立国際医療研究センター;株式会社ブリヂストン;独立行政法人国立循環器病研究センター
发明人:
中山 泰秀,石坂 幸人,根本 泰
申请号:
JP2006053110
公开号:
JP4968507B2
申请日:
2006.02.28
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
<;P>;PROBLEM TO BE SOLVED: To obtain a gene transfer agent enabling even gene transfer into a dormant cell such as a macrophage or lymphocyte. <;P>;SOLUTION: The gene transfer agent is obtained by adsorbing a peptide comprising C45(45-mer amino acid sequence segment) to a polyplex composed of a nucleic acid and a polymeric compound where multiple polymeric chains are introduced as substituents into an aromatic ring. Specifically, in this gene transfer agent, the aromatic ring consists of a monocyclic or condensed cyclic ring of 5-8C aromatic ring(s). More specifically, in this gene transfer agent, the polymeric chain is a polyacrylamide-based polymeric block chain or polyacrylate-based polymeric block chain. <;P>;COPYRIGHT: (C)2007,JPO&INPIT
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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