A physiology sensing device is adapted to be disposed on a living body. The physiology sensing device includes a driving unit, a sensing unit and a processing unit, wherein the sensing unit is connected to the driving unit and the processing unit is electrically connected to the driving unit and the sensing unit. The sensing unit is configured to sense a physiology information of the living body. The processing unit determines whether the physiology information is within a predetermined range. When the physiology information is beyond the predetermined range, the processing unit controls the driving unit to drive the sensing unit, so as to adjust a relative relation between the sensing unit and the living body.一種生理感測裝置,適於裝設於一生物上,生理感測裝置包含一驅動單元、一感測單元以及一處理單元,其中感測單元連接於驅動單元,且處理單元電性連接於驅動單元與感測單元。感測單元用以感測生物之一生理資訊。處理單元判斷生理資訊是否落在一預定範圍內。當生理資訊落在預定範圍外時,處理單元控制驅動單元驅動感測單元,以調整感測單元與生物間之一相對關係。1‧‧‧生理感測系統10‧‧‧電子裝置12‧‧‧生理感測裝置120‧‧‧通訊單元122‧‧‧驅動單元124‧‧‧感測單元126‧‧‧處理單元128‧‧‧輸出單元130‧‧‧加熱單元