Oliver Ast,Marina Bacac,Sabine Imhof-Jung,Christiane Jaeger,Christian Klein,Stefan Klostermann,Michael Molhoj,Joerg Thomas Regula,Wolfgang Schaefer,Pablo Umana
申请号:
US14816252
公开号:
US09914776B2
申请日:
2015.08.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.